De novo design of ligand binding proteins using large language models alone
Testing the ability of common large language models to consider design principles to generate de novo proteins that bind metals and lipophilic small molecules without copying existing sequences highlights the utility of LLMs in making protein design more comprehensible and accessible to users without sophisticated desi...
Nam Hyeong Kim, A. K. Hatstat, Hyunil Jo et al.
· bioRxiv · 0 citations