Author

Yin Shen

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Open access Sep 2026

3D epigenome of glial cell types in developing human cortex.

The human cortex is complex and heterogeneous, undergoing extensive expansion during development1,2. Our prior study of neurogenesis, including radial glia (RG), intermediate progenitor cells, excitatory neurons and interneurons demonstrated that chromatin looping underlies transcriptional regulation for lineage-specif...

Ian R. Jones, Li Wang, M. Kosicki et al. · Nature · 0 citations

#gene editing Open access Sep 2026

Interrogation of noncoding schizophrenia risk variants using CRISPR-based functional genomics

Findings show distinct noncoding mechanisms that map within GWAS signals, and provide a path forward for interrogating noncoding regulatory elements and variants in disease loci.

Marisa C. Hamilton, Julia W. Riley, Alexander C. Nelson et al. · bioRxiv · 0 citations