Author

Ying-Kui Tang

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Open access Oct 2026

Neutrophils orchestrate pre-metastatic immunosuppressive bone marrow remodeling during prostate cancer metastasis

The dynamic reprogramming of the bone marrow (BM) microenvironment during metastatic progression is poorly defined. Through single-cell profiling of BM samples spanning benign conditions, high-risk bone metastatic potential localized prostate cancer (HMP) and established bone metastatic prostate cancer (PCa), we uncove...

Ying-Kui Tang, Xuan Zhou, Duo-Cai Li et al. · bioRxiv · 0 citations

#machine learning Preprint Oct 2026

Proximal Causal Learning under Unmeasured Confounding

PCL-U is proposed, a framework that learns proxy variables directly from observed covariates and uses neural encoders to decompose covariates into treatment-inducing, outcome-inducing, and shared proxies, guided by minimax mutual information objectives and obtains causal estimates through a practical moment-based risk...

Ying-Kui Tang, Yi Wang · 0 citations