Induced pluripotent stem cell-derived chimeric antigen receptor natural killer cells: Engineering innovations, translational hurdles and clinical prospects in immune therapy
Induced pluripotent stem cell-derived chimeric antigen receptor natural killer (iPSC-CAR-NK) cells are an evolving off-the-shelf cellular immunotherapy platform with potential for scalable manufacturing, product standardization, and multiplex engineering.This review summarizes recent progress in clinical-grade manufact...