Author

Yong-Tang Zheng

2 papers indexed here

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Open access Sep 2026

mRNA Vaccines Targeting the Conserved SARS-CoV-2 Fusion Machinery Elicit Cross-Variant and Robust Immunity

Background/Objectives: Despite the gradual waning of global interest in SARS-CoV-2, the continued evolution and emergence of viral variants underscore the need for broadly protective vaccines. Vaccines targeting the highly mutable S1 subunit of the spike protein have shown limited breadth of protection, whereas conserv...

Jun Li, Ke-Meng Li, Shu-Heng Yu et al. · Vaccines · 0 citations

#protein folding Open access Sep 2026

STING-mediated JAK-STAT suppression drives CD4⁺ T cell dysfunction in aging people living with HIV-1

The rapidly growing population of older people living with HIV-1 (PLWH) continues to experience persistent immune dysfunction despite viral suppression, yet the underlying mechanisms remain unclear. To investigate the molecular basis of the unique immunological defects in these elderly PLWH, we performed t...

Na Li, Hong-Yi Zheng, Xia Li et al. · Immunity & Ageing · 0 citations