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Author

Yongjuan Zhao

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Open access Jan 2026

NRP1 silencing induces ROS-mediated cell cycle arrest and mitochondrial apoptosis in non-small cell lung cancer via upregulation of AGER

Highlights • NRP1 is significantly upregulated, whereas AGER is downregulated in NSCLC tissues.• Silencing NRP1 inhibits NSCLC cell proliferation and induces G1 phase arrest.• NRP1 knockdown triggers mitochondria-dependentk apoptosis and ROS accumulation.• AGER overexpression suppresses cell growth and mimics the effec...

Ya Yang, Ying Li, Yongjuan Zhao et al. · 0 citations

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