Context-Dependent Mechanisms of Oncologic Photodynamic Therapy: A Framework Linking Treatment Parameters to Cellular, Vascular, and Immune Responses
This critical narrative review applies a parameter–exposure state–mechanism–endpoint framework to oncologic PDT and distinguishes spatially restricted primary photochemical injury from downstream multicellular effects and appraises the evidentiary thresholds for immunogenic cell death (ICD) and systemic immune claims.