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Yoshiyuki Itoh

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#protein folding Case report Open access Oct 2026

Concurrent fibrinogen Aα-chain amyloidosis and AA amyloidosis in a Humboldt penguin (Spheniscus humboldti)

Amyloidosis is a disease characterized by the deposition of abnormally folded proteins as amyloid fibrils in tissues and occurs in various mammals and birds. In some cases, amyloids derived from two different precursor proteins may coexist in the same individual, a condition known as double amyloidosis. Amyloid A (AA)...

S. Iwaide, Natsumi Kobayashi, Mako Ikudome et al. · 0 citations
Open access Aug 2026

Systemic fibrinogen Aα-chain amyloidosis in a blue-winged kookaburra (Dacelo leachii): The first non-AA systemic amyloidosis in avians.

Amyloidosis is a group of protein-misfolding disorders characterized by the deposition of insoluble fibrils in tissues. In birds, only systemic amyloid A (AA) amyloidosis and cerebral Aβ amyloidosis have been described to date, and non-AA systemic amyloidosis has not been reported. We describe the first case of non-AA...

Tomoaki Murakami, Natsumi Kobayashi, Ayaka Shimmura et al. · 0 citations

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