Author

Yu-Xiang Zhou

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Open access Aug 2026

Proteo-genomics-guided interpretation of somatic mutations in cancer genomes.

By integrating protein structures with mutation data from 139,818 patients, this study generates detailed, functional maps of mutations for 173 cancer genes in 18+ tumor types, providing a proteo-genomic framework to characterize the effects of mutations in tumorigenesis and integrate them into workflows for clinical i...

D. Hyeon, Yu-Xiang Zhou, Wendy K. Chung et al. · Cancer Cell · 1 citation