Massively parallel characterization of RNA G-quadruplex stability and molecular recognition
RNA G-quadruplexes (rG4s) have been implicated as important regulators of RNA metabolism and are promising targets for RNA-targeted therapeutics. rG4s typically require a canonical (G≥2N1-7)4 motif, but the sequence features that affect rG4 stability and recognition by RNA-binding proteins (RBPs) and rG4-binding ligand...
Alli Jimenez, Rebekah L. Rothacher, Bryan B Guzmán et al.
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