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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yufei Zhang

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Aug 2026

Biosensor-driven Evolution and Transcriptome-Guided Chassis Engineering Enhance Endogenous l-Cysteine Supply for Ergothioneine Production.

An Escherichia coli platform for glucose-derived EGT production was developed by combining biosensor-driven evolution and transcriptome-guided chassis engineering, enabling sequential growth-based enrichment and fluorescence-based prioritization.

Su-Yu Wang, H. Zabed, Guoyan Zhang et al. · 0 citations
Jul 2026

Periplasmic Engineering Enhances Terminal Hydroxylation for Efficient Caffeic Acid Biosynthesis in Escherichia coli.

Caffeic acid (CA) is a valuable phenylpropanoid with applications in food, pharmaceutical, and chemical industries. Microbial production of CA is often limited by the terminal hydroxylation catalyzed by 4-hydroxyphenylacetate 3-monooxygenase (HpaBC). Here, we constructed a de novo CA biosynthetic pathway in Escherichia...

Shangyi Wang, Yuqi Zhuo, Jamila A Tuly et al. · 0 citations

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