Background: Whole-blood transcriptomic profiling can capture systemic immune-response alterations associated with COVID-19 and may support host-response-based classification. However, evidence regarding the discriminatory value of targeted immune-gene panels remains limited, and in small, high-dimensional datasets, the...
Z. Yilmaz, Z. Kucukakcali, Sami Akbulut· Viruses· 0 citations
Background: The Heart Failure Clinical Records dataset (n = 299) is among the most extensively reused benchmark datasets in clinical machine learning, yet the overwhelming majority of published analyses treat patient mortality as a static binary classification target and rarely test the statistical assumptions underlyi...
I. Cicek, Z. Kucukakcali· International Journal of Med...· 0 citations
Tree-based machine-learning models for dengue classification showed moderate discrimination, with high sensitivity but limited specificity, and yielded numerically higher AUROCs and lower Brier scores than the primary SMOTE-trained LR within this internal-validation framework.
Z. Yilmaz, Z. Kucukakcali, Sami Akbulut· Diagnostics· 0 citations
Under a leakage-controlled, unbiased evaluation, XGBoost provided moderate but trustworthy discrimination together with well-calibrated probabilities for diabetes prediction, while SHAP confirmed clinically plausible predictors.
Z. Kucukakcali, I. Cicek· International Journal of Med...· 0 citations
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