This comprehensive review explores advancements in the treatment of Triple-Negative Breast Cancer (TNBC), emphasizing the transformative impact of targeted therapies and immunotherapies. Given TNBC’s aggressive nature and limited therapeutic options, this review provides an in-depth analysis of emerging strategies that...
Gowhar Rashid, D. Elsori, Zainab Naqvi et al.· Frontiers in Oncology· 0 citations
INTRODUCTION/OBJECTIVE
Current cancer chemotherapy is limited by severe adverse effects, poor selectivity toward malignant cells, and the emergence of multidrug resistance, highlighting the need for novel therapeutic strategies with enhanced potency and safety. Sulfonyl-containing compounds and sulfonamide derivatives...
Faiz Ullah, Sami Ullah, M. Mustaqeem et al.· Current Medicinal Chemistry· 0 citations
BACKGROUND
Type 2 Diabetes Mellitus (T2DM) is a complex metabolic disorder characterized by insulin resistance and progressive β-cell dysfunction, although these mechanisms alone do not account for the considerable variability observed in disease presentation and clinical evolution. During the last decade, epidemiologi...
Ilderbayeva Gulzhan, Tatayeva Rosa, Tazhibayeva Damira et al.· Current Medicinal Chemistry· 0 citations
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