Author

Zeng-Bo Lu

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Review Sep 2026

Single-cell and Spatial Omics Reveal Spinal Cord Injury Microenvironmental Heterogeneity Relevant to Neural Interfaces and Spinal Neuromodulation.

OBJECTIVE Spinal cord injury (SCI) interrupts brain-spinal communication and causes persistent motor, sensory, and autonomic deficits. MATERIALS AND METHODS We summarize the current clinical and translational evidence on brain-computer interface (BCI)/epidural electrical stimulation (EES)/brain-spinal interface (BSI)...

Ming-Jie Lu, Jia-Wei Di, Ming-Zhu Deng et al. · Neuromodulation (Malden, Mas... · 0 citations

Jul 2026

PLIN2-PGAM5-regulated lipid droplet-mitochondria contacts drive microglial neuroinflammation after spinal cord injury via fatty acid metabolic reprogramming.

The findings identify the PLIN2-PGAM5 as a critical metabolic-immune pathway and suggest that targeting organelle-contact-mediated metabolic reprogramming represents a potential therapeutic strategy for CNS injury.

Daoqiang Huang, Hong Li, Yiqian Luo et al. · Cell Death and Differentiati... · 2 citations