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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Zhao-Le Chu

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Open access Sep 2026

Calcitriol alleviates ARID2-deficient gastric cancer metastasis via inhibition of the Wnt/β-catenin signaling pathway

Highlights • ARID2 mutation promotes the metastatic capability of GC.• Disruption of ARID2-VDR interaction activates Wnt/β-catenin signaling pathway.• VDR activation prevents ARID2-deficient GC metastasis by blocking nuclear β-catenin.• Calcitriol may represent a therapeutic candidate for ARID2-deficient GC metastasis.

Bi-Ying Liu, Zhao-Le Chu, Yi-Xian Fan et al. · 0 citations

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