Zhen-Yi Chen

Triple gene-knockout xenogeneic bone repair material achieves synergistic optimization of bone repair immunomicroenvironment and bone regeneration via antigen-immunity-inflammation axis modulation.

This study constructed a triple gene-edited and Urist-processed xenogeneic decalcified bone matrix system, offering an innovative gene-editing bone repair strategy to overcome immune rejection challenges in xenogeneic bone grafts and illuminates the therapeutic prospects of synergistically attenuating xenotransplantati...