Author

Zhenfei Zhang

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#protein folding Open access Sep 2026

Simplifying in silico protein evolution with minimal screening by unZipro.

UnZipro is presented, an efficient, scalable, and generalizable framework for zero-shot, in silico protein evolution, that integrates a compact, pre-trained inverse folding model with meta-learning to derive family-specific fitness landscapes.

Zhao-Hui Qin, Sanzeng Zhao, Zhao-Long Deng et al. · Molecules and Cells · 0 citations

Open access Jul 2026

Efficient homologous replacement and deletion of large genomic fragments through template‐jumping prime editing in rice

This study developed template‐jumping prime editing (TJ‐PE), a recently reported PE strategy for large targeted insertion, as an efficient tool for homologous replacement with DNA fragments ranging from dozens to hundreds of base pairs, and using TJ‐PE, replaced genomic fragments of up to 340 bp with homologous fragmen...

Huixia Liu, Yu Wang, Shuhui Guan et al. · New Phytologist · 0 citations