BACKGROUND/AIMS
Primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) are distinct diseases, yet many glaucoma cases in population-based datasets lack subtype specification. We assessed incidence patterns of glaucoma subtypes in China and the UK and used genetic evidence to infer the likely subty...
Charles Li, Bai-Han Wang, R. Walters et al.· British Journal of Ophthalmo...· 0 citations
BACKGROUND
Evidence regarding the effects of air pollution on bone damage remains limited and inconclusive. We aimed to investigate the individual and combined associations of long-term exposure to ambient air pollutants with fracture risk and bone mineral density (BMD).
METHODS
This study included 490,172 participan...
Hong-Jing Shi, Dong Sun, Xia Meng et al.· Journal of Hazardous Materia...· 0 citations
A role for lipid-driven chronic inflammation in IHD etiology is supported, and treatment strategies simultaneously targeting multiple lipid and inflammation pathways should be prioritized for further research to improve drug treatment of IHD beyond statin therapy.
Mohsen Mazidi, N. Wright, A. Pozarickij et al.· Journal of the American Coll...· 1 citation
These findings establish 24-hour wrist movement as a rich and scalable source of health information, with the potential to support passive health monitoring and disease prediction at population scale, and establish Sensori, a self-supervised foundation model that learns general-purpose health representations directly f...
Yong Wang, D. McGagh, K. Broomberg et al.· 0 citations
Long-term air pollution was associated with higher risks of clinically significant liver-related outcomes and a possible role of proteomic aging in the association between air pollution and liver-related outcomes is suggested, warranting further investigation.
An automated assay platform that robustly quantifies antibodies against up to 100 antigens in a single reaction, using Luminex suspension array technology, alongside generating ample quality control measures is described.
Lea Kröller, Rima Jeske, Birgitta E. Michels et al.· Nature Protocols· 1 citation
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