Overcoming Barriers to Heterologous Gene Expression Uncovers Regulatory Constraints in the Mucoralean Pathogen Rhizopus delemar
Rhizopus species are a leading cause of mucormycosis, an aggressive and life-threatening invasive fungal disease that affects immunocompromised individuals. Despite their clinical importance, mucoralean pathogens, especially R. delemar, are difficult to manipulate genetically because of coenocytic growth, multinucleate...