Tuberculosis (TB) is one of the deadliest infectious diseases worldwide, with complex and incompletely elucidated pathological mechanisms underlying its recalcitrance to cure. In recent years, the pivotal role of extracellular vesicles (EVs) in host-pathogen interactions has garnered increasing attention. This review s...
Wei Wang, Yi-Jia Liang, Qiu-Xia Gao et al.· Extracellular Vesicles and C...· 0 citations
These findings show that TDN + AIE@MM integrates physical sterilisation, immunosuppression reversal, and durable immune memory via dual spatiotemporal targeting, effectively addressing the three core challenges in TB therapy, namely delivery barriers, immune evasion, and relapse risk, and offering a promising strategy...
Wei Wang, Xiao-Xue Li, Mei-Jia Pan et al.· EBioMedicine· 0 citations
Cell-derived nanovesicles possess the capacity to cross the blood-brain barrier (BBB) and modulate the immunosuppressive tumor microenvironment (TME); however, the lack of efficient labelling probes limits their application in tracing biodistribution and achieving synergistic glioblastoma (GBM) theranostics. Herein, we...
