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Zhi-Ming Lu

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Open access Aug 2026

Therapeutic potential and underlying mechanisms of engineered young plasma-derived exosomes in Alzheimer's disease

Exosomes (EXOs) derived from the plasma of young individuals are believed to have the potential to ameliorate aging-related memory deficits. However, their specific roles and mechanisms in Alzheimer's disease (AD) therapy have not yet been systematically investigated. In this study, the rabies virus glycoprotein-target...

Hang Chen, Yuanquan Si, Qian Cheng et al. · 0 citations
Aug 2026

Transcriptome-wide association analysis of Alzheimer’s disease: construction and clinical validation of transcriptomic risk scores

The AD-specific transcriptomic risk scores (TRSs) developed in this study shows promising clinical utility in AD diagnosis, differential diagnosis, and risk prediction, providing valuable translational medical evidence for early screening and precision prevention of Alzheimer's disease.

Peng-Fei Zhang, Zhongqian Juan, Jia-Lin Han et al. · 0 citations

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