Author

Zhiqiang Yang

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Sep 2026

Amplification-Free Duplex Detection of Bacteria Using Solid-State Nanopores.

Rapid identification of bacterial pathogens remains challenging in clinical settings, particularly when timely decisions are required for acute or polymicrobial infections. Here, we report an amplification-free solid-state nanopore strategy for bacterial DNA detection using 12 nm silicon nitride nanopores and a minimal...

Shan Guo, Xiao-Bin Zhu, Sheng Zhang et al. · ACS Sensors · 0 citations

Open access Jul 2026

Bone-Targeted Nanosystems Induce Multiple Types of Cell Death and Suppress Osteoclasts via Sonodynamic Sensitization Therapy to Treat Bone Metastatic Tumors.

A metal-organic framework (MOF) sonosensitizer (PN20@Rx) for treating bone metastases was designed through alendronate sodium (ALN)-mediated defect engineering, which significantly increased sonocatalytic efficiency by narrowing the interstitial spaces and optimizing the sonic-to-electrical energy conversion.

Qingjian Lei, Zhiqiang Yang, Guangting Zhu et al. · Small · 0 citations