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Author

Zhigao Wang

2 papers indexed here

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Sep 2026

Biomimetic Silica Nanomotors Loaded with Food-Derived Antithrombotic Peptides for NIR Photothermal Efficient Clot Thrombolysis-Anticoagulation.

Here we report a fuel-free, all-optical platform that overcomes key limitations of conventional thrombolysis and offers a promising strategy for targeted, combined thrombolytic-anticoagulant vascular therapy based on food-derived bioactive substances. Thrombotic diseases remain difficult to treat because mature fibrin-...

Hui-Zhen Xing, Hui-Min Dong, Cheng-Zhi Guo et al. · 0 citations
Aug 2026

From In Silico De Novo Generation to In Vitro Functional Validation: Discovery of Multifunctional Antithrombotic Peptides from Food-Derived Proteins via a Hybrid LSTM-GCN and Molecular Simulation Pipeline.

Cardiovascular thromboses bring heavy global health burdens, while traditional screening of food-derived antithrombotic peptides is inefficient. This work built an integrated pipeline integrating de novo peptide generation, hybrid LSTM-GCN deep learning, and molecular simulations, screening 15,000 sequences to obtain l...

Hui-Zhen Xing, Hui-Min Dong, Cheng-Zhi Guo et al. · 1 citation

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