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Zhuangzhuang Yuan

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Aug 2026

Statins suppress colon tumors by inhibiting KRAS condensates.

The unclear regulatory and transport mechanisms of Kirsten rat sarcoma viral oncogene homolog (KRAS) limit a comprehensive understanding of KRAS activity and the development of inhibitors. Wang et al. reported that farnesylation-induced KRAS phase separation drives colon cancer progression and resistance to G12C inhibi...

Zhuangzhuang Yuan, Chenyu Wang, Rong Xiang · 0 citations

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