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Ziyan Nie

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Open access Sep 2026

PmWRKY‐10 Enhances Pine Wilt Disease Resistance by Promoting Pinosylvin Monomethyl Ether Biosynthesis Through Transcriptional Activation of PmPMT2‐1

ABSTRACT Pine wilt disease (PWD), caused by the pine wood nematode (PWN, Bursaphelenchus xylophilus), poses a severe threat to global pine forests. Plants can enhance their resistance to external stresses by eliciting secondary metabolites; however, the transcriptional regulatory mechanisms governing this defence respo...

Z. Nie, Shan-Shuo Hu, Bin Liu et al. · 0 citations
Open access Aug 2026

Pharmacological readthrough and base editing for ANK1 nonsense mutations in an erythroid model of hereditary spherocytosis

Findings provide exploratory proof-of-concept for targeted molecular intervention in ANK1 nonsense mutation-associated HS, highlighting TRIDs and ABEs as mechanistically distinct strategies with complementary strengths and limitations and suggesting their relative utility may depend on mutation-specific and clinical co...

Shan Li, Juan Li, Wen-Jing Shi et al. · 0 citations
#protein folding Open access Aug 2026

PtWOX2 and PtWOX14 accelerate somatic embryogenesis initiation in Pinus massoniana via synergistic hormonal and transcriptional reconfiguration

This study demonstrates that PtWOX2 and PtWOX14 significantly accelerate the initiation of somatic embryos in Pinus massoniana, offering a comprehensive molecular framework to address conifer recalcitrance via PtWOX -mediated synergistic hormonal and transcriptional reprogramming.

Kai Gao, Shan-Shuo Hu, Zhao-Ning Wang et al. · 0 citations

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