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diffusion models

237 papers

Prediction of Long-Term Postsurgical Seizure Recurrence From MRI Brain Hub Disruption in Patients With Temporal Lobe Epilepsy.

The model achieved high specificity in predicting long-term seizure recurrence, which supports its potential clinical utility for postoperative risk stratification and counseling rather than surgical exclusion and underscores the translational potential of network-level biomarkers to complement conventional predictors.

V.Yu. Karpychev, Rebecca W. Roth, William Yun et al. · 0 citations
#diffusion models Review Open access Sep 2026

Fragility fracture risk prediction using quantitative magnetic resonance and Vertebral Bone Quality scoring beyond density.

Assessment of quantitative MRI and VBQ/modified VBQ into predictive models enables opportunistic, radiation-free screening and more precise fracture risk assessment, bridging the gap between bone quantity and quality for improved prevention and management of fragility fractures.

Sanjith Manian, Arunagiri Gunasekar, Naveen Jeyaraman et al. · 0 citations

Modeling Environmentally Driven Seasonal Moisture Migration and Ground Movements in Expansive Clays

This paper describes the formulation of a numerical model for simulating environmentally driven one-dimensional (1D) ground movements of expansive clay. The formulation is based on a finite-element model that simulates the redistribution of matric suction through a diffusion-type equation, explicitly accounting for volume changes due to wetting and drying of the clay. We synthesize and modify highly nonlinear constitutive relationships for (1) hysteretic soil water retention; (2) reversible soil shrinkage and expansion of clay; and (3) hydraulic conductivity, explicitly incorporating desiccation cracks through a multidomain framework and assuming a critical surface crack depth. These models are well-calibrated to published laboratory tests on a reference expansive clay, Denver bentonite. We demonstrate capabilities of the proposed formulation to simulate the response of a homogeneous expansive clay to periods of drying and wetting, considering the initial matric suction, saturated hydraulic conductivity of the intact clay, and critical crack depth as three primary sources of uncertainty. We compare ensemble model simulations with measured ground movements from an instrumented expansive clay test site in Texas over a 3-year period using detailed records of potential evapotranspiration and precipitation. By assigning weights to the ensemble simulations based on their performance, we constrain the ranges of the three key uncertain parameters. The results showed very reasonable first-order agreement with the measured data and highlight the potential of the proposed formulation. We anticipate that more reliable predictions can be achieved through direct measurements of actual in situ evaporation rates and local soil properties.

Mahdi Seyyedan, Jiali Ma, Ivo Rosa Montenegro et al. · 1 citation

Enhancing salt and moisture diffusion in beef by ultrasound-assisted tumbling: Insights from mathematical modeling, hyperspectral imaging, and finite element analysis.

This study aimed to explore the influence of ultrasound-assisted tumbling on mass transfer efficiency during beef brining. One-dimensional mathematical modeling for kinetic simulation, two-dimensional hyperspectral imaging for visualization, and three-dimensional finite element analysis for spatial diffusion simulation were respectively adopted to characterize the diffusion dynamics of salt and moisture in beef. Results indicated that ultrasound-assisted tumbling significantly increased the diffusion coefficients of salt and moisture (p < 0.05). Compared with diffusion, Peleg, Azuara, and Zugarramurdi-Lupín models, the Weibull model was identified as the most effective one in predicting the diffusion kinetics of salt and moisture (Rs2 ≥ 0.990, Rm2 ≥ 0.987). The visualization results of two-dimensional hyperspectral imaging and three-dimensional finite element simulation consistently indicated that the distribution of salt and moisture dynamically evolved during diffusion, exhibiting transient and irregular features, thereby reflecting the complex and nonlinear nature of mass transfer in meat. This study provides new insights and approaches for investigating the diffusion behavior of brine in meat products.

Lei Jin, Lei Zhou, Ruyu Zhang et al. · 0 citations
#diffusion models Open access Oct 2026

Seismicity migration from fluid injection: Laboratory experiments and numerical models illuminate volume-driven versus pressure-diffusion-driven migration

23 Fluid injection into the subsurface can induce seismicity by reactivating shear rupture, which 24 typically produces larger earthquake magnitudes than tensile rupture. In laboratory shear 25 rupture experiments, pressurization of the entire fault is often limited because large unconfined 26 samples allow fluid to leak at free surfaces. In this study, we investigated shear fault 27 reactivation by directly injecting fluid into a PMMA fault (760 mm long, 76 mm high) formed 28 as the interface between two separate PMMA blocks. To prevent leakage in the 76 mm 29 dimension, we made a low permeability barrier by coating the outer edges of the fault with 30 Teflon tape. Fluid pressure then extended along the 760 mm dimension, resulting in the 31 migration of seismicity away from the injection well. Changes in injection rate and fluid 32 viscosity revealed two mechanisms: (1) slow injection rate or low-viscosity fluid caused 33 seismicity migration governed by pressure diffusion, and (2) fast injection rate or high-34 viscosity fluid caused seismicity migration proportional to injected volume. Simulations with 35 a 2D poroelastic model showed that seismicity migrated with the fluid pressure front in the 36 volume-driven regime, whereas fluid pressure advanced well ahead of seismicity in the 37 pressure-diffusion-driven regime. These results highlight that Teflon tape effectively sealed 38 faults and controlled fluid flow, and that injection rate and fluid viscosity have a strong impact 39 on fault slip and induced seismicity. 40

Jun Young Song, Lingfu Liu, C. Arson et al. · 0 citations

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Microsoft Research Blog Aug 31, 2026

GigaPath-Flash and GigaTIME-Flash: Toward population-scale discovery with efficient pathology foundation models

What if pathology foundation models could do more with less? GigaPath-Flash and GigaTIME-Flash cut computational demands while maintaining strong performance, opening the door to larger studies and broader exploration. The post GigaPath-Flash and GigaTIME-Flash: Toward population-scale discovery with efficient pathology foundation models appeared first on Microsoft Research.