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18,068 papers
Biological function in RNA is encoded across scales, from local sequence motifs to long-range structural dependencies. Conventional RNA foundation models couple parameter capacity and inference depth within a fixed architecture, prescribing a fixed computation graph for each inference. Here we present Eco-RNA, an 80M-p...
Failure attribution for LLM agents aims to identify decisive steps responsible for task failure, which is critical for debugging and improving agentic systems. Existing methods rely on costly LLM prompting, step-level error annotations, or verified successful trajectories that lack failure signals for assistance. In th...
Large language models (LLMs) are increasingly being explored as facilitators of group discussion and collaborative work, but the behavioral differences between LLM-generated and human facilitation remain insufficiently characterized. We compare human Project Manager facilitation turns from scenario-based collaborative...
Processing a long sequence does not guarantee that distant information remains usable. As context grows, a fixed-size memory must retain many associations, connect information across positions, and preserve relevant structure without being overwhelmed by everything it observes. These are distinct requirements: a memory...
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Large Language Model (LLM) agents have demonstrated remarkable capabilities in tackling complex tasks through agentic workflows. However, manually designing these workflows is labor-intensive and lacks flexibility to adapt to diverse queries. While automated workflow optimization is a promising direction, existing meth...
Evaluating deep learning optimizer is challenging because confounding factors such as hyperparameter tuning and optimizer-model co-design often obscure true algorithmic performance. We present results of the updated AlgoPerf V1 benchmark, in which we evaluate a new set of training algorithms on wall-clock time-to-targe...
Trajectory extrapolation from a partial target trajectory is underdetermined, but completed related trajectories provide information about the unresolved continuation. We propose target-constrained pooling (TCP), which separates the finite-horizon endpoint from continuation shape and estimates that endpoint from two co...
Neural operators that learn physical laws from data should generalize beyond their training distribution and expose the learned law in closed form. The Kolmogorov-Arnold neural operator achieves both for position-dependent dynamics by learning a dense pseudo-differential symbol over all positions and frequencies, at a...
Reinforcement learning (RL) has become a dominant paradigm for enhancing LLMs' reasoning capabilities. Yet long-horizon autoregressive rollouts introduce a fundamental limitation: local policy mismatch can compound into severe state distribution shift over trajectories. Existing LLM RL methods, such as GRPO and GSPO, c...
Softmax-based multimodal emotion recognition methods often assign high confidence even when sensor data are corrupted or contradictory, for example when facial expressions suggest positive valence while vocal prosody indicates negative arousal. We present an Evidential Multimodal Transformer with Dempster-Shafer Fusion...
We study how offline data can help online learning in stochastic linear bandits. We focus on partially covered offline data, where only $k$ of the $d$ feature directions are poorly covered. Existing analyses of algorithms based on phased elimination and optimism give regret bounds of order $\widetilde O(\sqrt{dkT})$ in...
Accurate daily precipitation forecasts are important for weather-sensitive decisions. Although recent Weather Foundation Models (WFMs) have achieved significant progress, they are trained on reanalysis data, which exhibit regional and intensity-dependent biases. Since retraining WFMs on observation-based targets is cos...
The new approach, known as FLEX, could lead to more intuitive, interactive household and assistive robots.
By learning how matter moves, the WorldParticle system could assist with developing soft robots, medicines, and more.
A machine-learning approach called CheMeleon provides a practical way to develop new drugs or other molecules with much less detailed, expensive experimentation.
A Blog post by Ai2 on Hugging Face
Research Manager Mike Walker reflects on a career spanning hacker culture, cybersecurity, and AI, sharing lessons about trust, teamwork, leadership, and why solving difficult problems requires curiosity, judgment, agility—and an understanding of the rules. The post Learn the rules: The hacker mindset appeared first on Microsoft Research.
Learn how Google Antigravity and our Cheminformatics Skills accelerate drug discovery workflows, search compounds, and propose novel rigidified macrocycles.
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