Genomic Characterization and Therapeutic Potential of the Lytic Bacteriophage Curly against Klebsiella pneumoniae in Human Innate Immune Cells and a Murine Pneumonia Model

Mounika Duggineni S. Adduri Rajesh Mani Leticia Guzmán Ruiz Andy Omeje Narendra Kumar Gonepudi J. Kleam Mounika Kumaraswamy J. Dennehy Guohua Yi

Aug 2026 · bioRxiv · 0 citations · 39 references

Biology

TL;DR

Findings identify Curly as a promising bacteriophage candidate against K. pneumoniae and support further evaluation of its host range, resistance profile, and therapeutic potential.

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