Diagnostic performance of quantitative flow ratio against intravascular ultrasound in left main coronary artery disease: a prospective single-centre study.

Head-to-Head Comparison of Quantitative Flow Ratio, Intravascular Ultrasound, and Coronary Angiography in Left Main Coronary Artery Disease.

BACKGROUND Intermediate left main coronary artery (LMCA) disease poses a significant diagnostic challenge. Intravascular ultrasound (IVUS) is the guideline-recommended reference standard for anatomical assessment, whereas quantitative flow ratio (QFR) provides a wire-free physiological estimate. Conventional coronary a...

Diagnostic Accuracy and Feasibility of Quantitative Flow Ratio at Low Frame Rate Angiography: The Prospective Multicentre Australian AVALON Study.

BACKGROUND Quantitative Flow Ratio (QFR) is a well-established, non-hyperemic, angiographic, wire-free predictor of ischemia when compared to Fractional Flow Reserve (FFR). However, its diagnostic accuracy at low frame rates (< 10 frames/second), commonly used in contemporary practice to minimize radiation exposure, ha...

Diagnostic performance of computed tomography-derived fractional flow reserve in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a single-centre feasibility study.

Computed tomography-derived fractional flow reserve (CT-FFR) provides good diagnostic performance for detecting haemodynamically significant CAD in TAVI candidates and integration into routine workflows may reduce purely diagnostic invasive procedures while maintaining accuracy.

Comparison of wire-based hyperaemia-induced fractional flow reserve (FFR) and angiography-based vessel fractional flow reserve (vFFR) in patients undergoing physiological assessment of coronary lesions.

OBJECTIVE While pressure-wire based fractional flow reserve (FFR) is considered the gold standard for evaluating coronary lesion significance, its use in daily clinical practice remains limited.Angiography derived vessel based FFR (vFFR) offers a promising alternative, without the need for pressure wires or hyperaemia...

Diagnostic Accuracy of Quantitative Coronary Analysis as Compared with Instantaneous Wave-Free Ratio in Intermediate Coronary Lesions: A Prospective Vessel-Level Study

Background Instantaneous wave-free ratio (IFR) represents a new vasodilator-free innovative approach which is considered as a gold standard for functional assessment of the hemodynamic significance of intermediate coronary stenoses. Although relatively safe, iFR is still an invasive procedure that has its potential haz...

Diagnostic performance of CT-derived fractional flow reserve across coronary lesion morphologies: a prospective multicenter study.