SpermYOLO: A Coordinated YOLO-Based Detector for Accurate and Efficient Sperm and Impurity Detection in Microscopic Images

Abstract

Accurate sperm detection is essential for computer-assisted semen analysis, yet it remains challenging in microscopic images due to dense distributions, visually similar artifacts, and sperm-like impurities. In this paper, we propose SpermYOLO, a coordinated and compact YOLOv11-derived framework for joint sperm and impurity detection in microscopic images. SpermYOLO introduces four architectural improvements: C3k2-IDB for channel-wise discriminative feature extraction, D2SEM for spatial--spectral semantic enhancement, MFM for adaptive multi-scale feature fusion, and the DESD Head for detail-enhanced shared prediction. Experiments on the SVIA semen microscopic imaging benchmark show that SpermYOLO achieves 97.2\% sperm AP and 75.4\% impurity AP, outperforming generic detectors, dedicated sperm detection models, and improved YOLO variants. Compared with the baseline model, SpermYOLO improves sperm AP, impurity AP, $\mathrm{mAP}_{50}$, and $\mathrm{mAP}_{50:95}$ by 1.6, 10.0, 5.8, and 2.7 percentage points, respectively, while preserving a lightweight model scale. Cross-scene evaluation on the SDTB testicular-biopsy microscopy benchmark shows that SpermYOLO remains effective with extremely small sperm targets and complex tissue backgrounds, achieving the highest $\mathrm{mAP}_{50}$ and $\mathrm{mAP}_{50:95}$ of 74.8\% and 31.2\%, respectively. Ablation studies and qualitative analyses further support these improvements by demonstrating the contributions of the proposed modules and showing more focused feature response patterns than the baseline model. These findings suggest that SpermYOLO is an effective and efficient approach for sperm detection in challenging microscopic imaging scenarios.