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#gene editing Open access

Efficient genome editing in tomato using Cas12i3 variants.

Si-Qun Wu Lei Zhu Mei-Li Zhou Bo Yu Jin-Kai Li Xiao-Mu Niu Peng-Cheng Wang Jian-Kang Zhu Zhao-Bo Lang
Sep 2026 · Journal of Integrative Plant Biology · 0 citations · 9 references
Medicine

Abstract

Systematic comparison of Cas12i gene-editing tools in tomato identifies Cas-SF01 as the most efficient variant, achieving editing efficiencies comparable to conventional Cas9 at some genomic sites and providing a compact, highly specific, and versatile tool for studying gene function, engineering fruit metabolism, and developing improved tomato varieties through precision breeding.

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