Polycyclic aromatic hydrocarbons exposure and hyperuricemia: insights from China-Northern Anhui Coal workers Cohort study to network toxicology analysis
Aug 2026· Environmental Geochemistry and Health· Vol 48· 0 citations· 49 references
Medicine
TL;DR
It is emphasized that inflammation-related genes may be involved in the adverse effect of PAHs on HUA risk among coal workers and network toxicology highlighted inflammation-related genes and IL-17 pathway as possible toxicological mechanism linking PAHs exposure and HUA.
Mixed exposure to PAHs, BTX, and metals increased MetS risk more than single pollutants, highlighting their importance for future occupational health monitoring and risk management.
Occupational PAH exposure is modestly associated with upper gastrointestinal cancer risk, particularly esophageal cancer, with higher risk estimates observed in high-exposure occupations.
M. S. Seyyedsalehi, Anna Vrtev, M. Lanza et al.· European Journal of Cancer P...· 0 citations
Low-to-moderate urinary arsenic exposure may be associated with altered LDL-C levels and increased UACR, with species- and population-specific differences, with species- and population-specific differences.
Di Wu, Shirui Yan, Xinxiao Li et al.· Frontiers in Endocrinology· 0 citations
Investigating the systemic biological effects of occupational exposure to PAHs from asphalt fumes in road construction workers revealed profound alterations in pteridine metabolism and activation of the kynurenine pathway, using a combined panel of exposure and mechanistic biomarkers.
T. Baydar, S. Palabiyik-Yucelik, G. Girgin et al.· Chemical Research in Toxicol...· 0 citations
When stratified by seafood type, raw and high omega-3 fish intake showed the strongest associations with urinary and serum metabolomes, while fried fish had weaker or non-significant correlations, suggesting that cooking methods may modulate the bioavailability or metabolic impact of fish nutrients.
T. Byambajav, Queenie Chan, Yukiko Okami et al.· European Journal of Nutritio...· 0 citations
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