The effects of stress hormones on the immune system are investigated using single-cell RNA sequencing to better understand how stress-regulated immunological signaling contributes to disease.
Abstract
Connections between chronic stress, inflammation, and human diseases are well-established but poorly understood. In this issue of Cell Genomics, the effects of stress hormones on the immune system are investigated using single-cell RNA sequencing to better understand how stress-regulated immunological signaling contributes to disease.
There is significant evidence that, in neurodegenerative disorders, oxidative stress in the brain is fundamental to the pathophysiology and progression of such conditions, among which is Alzheimer disease (AD) [...].
Evidence is provided for a key role of TNFR1, as expressed by malignant cells, in orchestrating a pro-tumor immunosuppressive environment through secondary inflammatory mediators through secondary inflammatory mediators.
Elixabet Bolaños, Lorena Cañas-Zabala, Irene Olivera et al.· Journal of Experimental Medi...· 0 citations
Low-molecular-weight metabolites are attracting attention as a group of molecules that play important roles in immune cell function. Recent studies have revealed that metabolites actively regulate immune cell differentiation and function rather than simply reflecting metabolic status. This overview focused on metabolit...
