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Review Open access Sep 2026

Food Matrix as a Modulator of Spice Phytochemical Bioactivity: Evidence from In Vitro, Animal, and Human Studies

Spices contain numerous bioactive compounds with antioxidant, anti-inflammatory, antimicrobial, and metabolic effects. However, their biological activity depends strongly on the food matrix, which influences phytochemical stability, bioaccessibility, and physiological responses. This review evaluates the complex intera...

Karolina Rak, P. Serek, Paulina Sławińska et al. · 0 citations
Review Aug 2026

The role of the food matrix in peptide bioavailability: a review of interactions and their impact on absorption.

This review assesses the critical role of the food matrix (FM) in regulating peptide bioavailability, addressing the new challenge of overcoming low oral absorption of diverse peptide classes and advocating for matrix-engineered delivery systems (such as microencapsulation and probiotic fermentation) to establish a hol...

Chunhong Liu, Chao-Qing Wen, O. Olatunji et al. · 2 citations
Review Sep 2026

Postbiotic Metabolites: Therapeutic Potential, Industrial Applications, Market Dynamics, and Regulatory Frameworks.

The need for well-designed clinical studies, standardized regulatory guidelines, and interdisciplinary research to support the effective use of postbiotics in precision medicine and personalized nutrition is underscored.

Atru Gnana Surya Chandu, Akula Nagarjuna, Abinaya Soundar et al. · 0 citations
Review Open access Aug 2026

Bioavailability of dietary polyphenols and plant bioactives in functional foods: insights and limitations from in vitro digestion models

This review provides a comprehensive evaluation of how bioactive compounds within plant- and animal-derived food matrices interact with human physiology and metabolic pathways, with a particular focus on secondary metabolites synthesized or transformed via microbial pathways. The manuscript covers a diverse range of li...

M. E. Ibrahim, Utku Benan Usta, Seydi Yıkmış et al. · 0 citations
Review Open access Aug 2026

Plant Protein-Derived Bioactive Peptides: From Mechanistic Promise to Health-Promoting Functional Foods

The evidence indicates that peptide discovery should not be treated as the principal endpoint of research, and future progress will require translation-oriented development in which bioactivity, digestion stability, matrix compatibility, sensory quality, manufacturing reproducibility, realistic intake, human evidence,...

M. Czernicka, Patrycja Sowa-Borowiec, A. Wondołowska-Grabowska · 1 citation
Review Open access Oct 2026

Edible Mushroom Polysaccharides as Functional Food Ingredients for Metabolic Health: Preparation, Techno-Functional Behavior, and Requirements for Translation

Edible mushroom polysaccharide (EMP) preparations have repeatedly improved glycemic control, adiposity, lipid homeostasis and hepatic lipid accumulation in animal models, and luminal assays and microbiota-perturbation experiments support the routes involved. Selected preparations also thicken, emulsify, retain water an...

Ming Chen, Rui-Fan Zou, Jie Chen et al. · 0 citations

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