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Open access

The role of polygenic risk in Alzheimer's disease prediction for African Americans

Christina G. Hutten Todd Beck Denis A. Evans K. Rajan
Aug 2026 · Alzheimer's & Dementia · Vol 22 · 0 citations · 64 references
Medicine

Abstract

African Americans (AAs) face a higher risk of Alzheimer's disease and related dementias (ADRD) than European Americans (EUs), yet the utility of polygenic risk scores (PRS) in AAs remains underexplored.

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