TL;DR
The results indicate the high potential of vB_EfaP_2/Chl-5 for treating infections caused by E. faecium, and shows that phage vB_EfaP_2/Chl-5 effectively targets biofilms in vitro, reducing the number of viable cells.
The emergence and spread of Gram-negative pathogens that are resistant to multiple antibiotic classes pose a global risk to public health. Among such pathogens, carbapenem-resistant strains of Klebsiella pneumoniae (CR-KP) are of concern due to their resistance to treatment by most antibiotics and the mobility of their...
Introduction Vibrio harveyi is a major pathogen causing skin ulceration syndrome and mass mortality in sea cucumber Apostichopus japonicus aquaculture. Methods In this study, a pathogenic strain NB-3 was isolated from diseased A. japonicus and identified as V. harveyi based on morphological, physiological, and genomic...
These findings identify two novel lytic Enterobacter phages and support a narrow EDTA concentration window for enhanced phage‐mediated antibiofilm activity.
The objectives of this study were to isolate, characterize, and evaluate the biocontrol potential of Staphylococcus aureus-targeting bacteriophages in milk. From wastewater and raw milk samples, a total of 19 lytic phages were isolated. Among them SAKAY1298 and SAKAY1306 phages were selected for detailed phenotypic and...
The potential of SAP_2 as a biocontrol candidate for controlling MRSA contamination in milk is supported and good biosafety and reduced bacterial burdens in MRSA-infected mice are exhibited.
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