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Review

Precision Oncology in Melanoma and Skin Cancer Surgery.

Oct 2026 · Hematology/Oncology Clinics of North America · Vol 40 5, pp. 857-873 · 0 citations · 95 references
Medicine

TL;DR

With breakthrough findings in such a relatively short period of time, the treatment of patients with metastatic melanoma has become intensely personalized.

Abstract

There has been perhaps no greater advance in the prognosis of solid tumors in the last decade than for patients with metastatic melanoma. This is due to significant improvements in treatment based on two key components of melanoma tumor biology (1) the identification of driver mutations with therapeutic potential and (2) the mechanistic understanding of a tumor-specific immune response. With breakthrough findings in such a relatively short period of time, the treatment of patients with metastatic melanoma has become intensely personalized.

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