TL;DR
This study provides a candidate lncRNA resource and prioritizes lncRNA-associated gene pairs potentially related to life-cycle reversal in T. dohrnii as a candidate lncRNA resource.
A chromosome-level genome assembly of C. arabica revealed that protein-coding homeologs are predominantly co-regulated between subgenomes, and intergenic lncRNAs display a modest, but statistically consistent bias toward subgenome E across diverse developmental and stress contexts.
A lncRNA‐mRNA co‐expression network associated with lignin biosynthesis was established and the regulatory role of lncRNA‐pys within this network was functionally validated through transgenic experiments, demonstrating that overexpressing lncRNA‐pys led to an increase in lignin content in pear.
It is proposed that the upregulated lncRNA ENSG00000265613 may enhance malignancy by stabilizing the RNA target ENSG00000582008 in luminal A breast cancer, particularly given its established role in oncogenesis.
It is demonstrated that lncRNAs constitute an important regulatory layer controlling specialized metabolism in tea plants and reveal a transposon-derived lncRNA that modulates catechin biosynthesis.
It is demonstrated that lncRNA50877 disrupts mitochondrial homeostasis by negatively regulating KRT8 expression, thereby modulating ROS levels, apoptosis, and autophagy; promoting oxidative stress-induced cell injury; and providing favorable conditions for GCRV replication.
This chapter explores the biomedical significance of ceRNAs, highlighting their role in modulating gene expression and their potential implications in disease, and summarizes available tools, resources, and practical examples for studying lncRNA-miRNA interactions to aid researchers in navigating this sophisticated reg...
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