maniFasta and the AllOralsDB: simplifying construction of comprehensive reference databases for metaproteomics

Christopher Handelmann Ashley K. Miles Yin-Yin Ye Marcelo Freire F. E. Dewhirst Tsu-Te Chen J. M. Mark Welch Kathryn M. Kauffman

Aug 2026 · bioRxiv · 0 citations · 94 references

Biology

TL;DR

ManiFasta is presented, a tool enabling users to generate standardized, reproducible, and robustly documented protein reference sets from diverse input sources and datatypes, and the value of maniFasta is highlighted in the context of salivary metaproteomics, addressing the need for a taxonomically comprehensive reference database.

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