Early-Onset Appendiceal Adenocarcinoma (Age < 50 Years): Temporal Trends in Case Proportions, Histologic Patterns, and Survival Outcomes From SEER, 2000-2023.
Aug 2026· Annals of Surgical Oncology· 0 citations· 14 references
Medicine
TL;DR
Early-onset appendiceal adenocarcinoma accounts for approximately one in five cases nationally and carries distinct demographic and histologic features and survival was shown to be driven primarily by stage and tumor characteristics rather than by age alone.
Early-onset CMA presented with different demographic and disease characteristics and treatment patterns than later-onset disease, and survival of early-onset CMA was higher than later-onset CMA.
S. Emile, Spencer Barnes, Z. Garoufalia et al.· Journal of Gastrointestinal...· 0 citations
EO-SBNETs represent a rising and clinically distinct subgroup characterized by similar presentation and treatment but relatively favorable long-term outcomes compared with AO-SBNETs, suggesting potential biological differences warranting further investigation.
Matthew T. Gao, Rishi R. Patel, Jason Semprini et al.· American Journal of Clinical...· 0 citations
INTRODUCTION
The global rise in early-onset colorectal cancer (EORC) contrasts with declining rates in older adults, suggesting emerging environmental and biological influences. Data from non-Western populations, particularly India, remain scarce despite a young demographic and distinct tumor biology.
METHODS
A retro...
A. Saklani, M. Kazi, Prudvi Raj et al.· European Journal of Surgical...· 0 citations
Background Despite growing awareness of the rising incidence and particular features of early-onset gastrointestinal cancer (EOGIC), evidence from Spain remains limited. The purpose of this study was to compare EOGIC with average-onset gastrointestinal cancer (AOGIC) in Navarre, by analysing incidence trends, clinicopa...
I. Cáseda, A. Huerta, A. Lecumberri et al.· ESMO real world data and dig...· 0 citations
BACKGROUND
Nonmalignant intracranial meningiomas are common primary CNS tumors with favorable prognosis, yet survival patterns across adulthood remain incompletely characterized. This study aims to evaluate age-stratified overall survival according to sex, race, ethnicity, tumor size, and surgical history.
METHODS
Th...
Tiffany M. San, Collin W. Soderstrom, Carolina Lopes et al.· World Neurosurgery· 0 citations
Background The incidence of adenocarcinomas of the distal esophagus, gastroesophageal junction (GEJ), and stomach diagnosed before age 50 years is increasing and early-onset disease may have a distinct phenotype. A comprehensive synthesis of clinicopathological and molecular differences between early-onset and average-...
F. Petrelli, L. Dottorini, S. Cherri et al.· ESMO gastrointestinal oncolo...· 0 citations
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