Intranasal immunization in mice with spore-associated serine-aspartate repeat-containing protein D from Staphylococcus aureus secreted in Bacillus subtilis
Findings demonstrate that B. subtilis can serve as an effective platform for recombinant protein secretion and mucosal antigen delivery, supporting its application in vaccine development against S. aureus infection via mucosal route.
Genetic analysis of the SAUSA300_1739 to SAUSA300_1744 operon across several Staphylococcus aureus strains indicate that the operon is highly conserved, highlighting its importance for virulence.
Alex Zilinskas, H. M. Ni, Zoe Netter et al.· bioRxiv· 0 citations
ABSTRACT Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA) are ESKAPE pathogens that are responsible for severe skin and soft tissue infections (SSTIs), particularly in the elderly and those with immunocompromising conditions. Rising rates of methicillin-resistant S. aureus (MRSA) and carbapenem-resistant PA h...
Suhrid Maiti, T. Lu, Zackary Dietz et al.· Infection and Immunity· 0 citations
The potential of SAP_2 as a biocontrol candidate for controlling MRSA contamination in milk is supported and good biosafety and reduced bacterial burdens in MRSA-infected mice are exhibited.
Dong-Xin Ma, Shuai-Feng Gu, Yu-Qiang Zhang et al.· Current Research in Food Sci...· 0 citations
It is demonstrated that D. pigrum limits S. aureus through both host immune modulation and direct suppression of bacterial pathogenesis and adaptive fitness, supporting its potential as a microbiota-based therapeutic adjuvant to enhance antibiotic efficacy against S. aureus -associated infections.
Chun-Chi Chang, Tomas Demeter, A. Gómez-Mejia et al.· Microbiome· 1 citation
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
