TL;DR
Combined assessment of IL-10 gene expression, CRP, and NT-proBNP may improve inflammatory–cardiac risk stratification in CMS and significantly associated with the presence of HF among patients with CMS.
BACKGROUND Inflammation plays a crucial role in adverse outcomes of coronary artery disease. NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome activates 2 classical pathways: interleukin-1β (IL-1β)/IL-6/high-sensitivity C-reactive protein (hsCRP) and IL-18/IL-6/hsCRP. However, the predicti...
Atherosclerotic cardiovascular disease (ASCVD) is a chronic inflammatory disease characterized by plaque formation. Inflammatory activity, assessed by high-sensitivity C-reactive protein (hsCRP), is linked to increased ASCVD risk. Recently, there has been much interest in the association between interleukin-6 (IL-6), a...
Aim . To compare the concentrations of pro-inflammatory (interleukin (IL)-1β, IL-6, tumor necrosis factor-α) and anti-inflammatory (IL-4, IL-10) cytokines, as well as leptin and adiponectin, and to evaluate their independent associations with anthropometric, metabolic, and echocardiographic parameters in patients wi...
Elevated ET-1, IL-6, and IL-18, along with ET-1 polymorphism, suggest synergistic genetic-inflammatory mechanisms in CAD progression among diabetic-hypertensive patients and multi-marker profiling improves early CAD detection.
INTRODUCTION Osteoporosis is a metabolic disorder characterized by reduced bone mass and microarchitectural deterioration, and it is closely associated with inflammatory processes. This study investigated the expression of microRNA-146a (miR-146a), interleukin-31 (IL-31), and interleukin-33 (IL-33) in osteoporosis and...
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