A framework in which an AI builder turns a scientific brief into an executable AI lab: a task-specific solver that integrates models, knowledge resources, tools, and a controller behind a fixed interface is presented.
Abstract
Scientific tasks specify a desired capability, but realizing it often requires building a computational system tailored to the task---acquiring data, designing representations, training models, implementing tools, and deciding how they are used at inference. We present, a framework in which an AI builder turns a scientific brief into an executable AI lab: a task-specific solver that integrates models, knowledge resources, tools, and a controller behind a fixed interface. The builder develops and packages the lab in a metered workspace; a separate host then executes the delivered artifact on held-out inputs, with reference labels kept outside the solver's input interface, and scores its outputs under the task's protocol. This makes the delivered system, rather than the builder's account of its progress, the object of evaluation. We document 10 selected constructions across six scientific task categories---from molecular and genomic prediction to medical imaging, clinical decision support, and biomedical text---whose delivered labs exceeded their configured reference values on all 12 subtests under host-side execution. Four contain predictive models fitted during construction; the others assemble executable analysis environments, knowledge resources, and tool-driven workflows around a fixed platform LLM. Together they show that an AI agent can carry a scientific brief all the way to a working lab that can still be invoked, inspected, and checked after construction ends.
The results indicate that software engineering work practices are chosen opportunistically, adapted and configured to provide value under the constrains imposed by the startup context.
Nicolò Paternoster, Carmine Giardino, M. Unterkalmsteiner et al.· Information and Software Tec...· 394 citations· ⚡54
The possibility of inferring high-dimensional data inference in a model that consists of a prior and an auxiliary differentiable constraint given some additional information is considered, thereby allowing a range of potential applications in adapting models to new domains and tasks.
Alexandros Graikos, Esmeralda S. Whitammer, N. Jojic et al.· Neural Information Processin...· 316 citations· ⚡15
It is proved that any global minimizer of the trajectory balance objective can define a policy that samples exactly from the target distribution, and empirically demonstrate the benefits of the trajectories balance objective for GFlowNet convergence, diversity of generated samples, and robustness to long action sequenc...
Esmeralda S. Whitammer, Moksh Jain, Emmanuel Bengio et al.· Neural Information Processin...· 302 citations· ⚡60
This state-of-practice investigation was performed using a literature review followed by a multiple-case study approach and presents how inconsistency between managerial strategies and execution can lead to failure by means of a behavioral framework.
Carmine Giardino, Xiaofeng Wang, P. Abrahamsson· International Conference on...· 175 citations· ⚡19
This work investigates the possibilities of using LLMs in a resume screening setting via a document retrieval framework that simulates job candidate selection and finds that the MTEs are biased, significantly favoring White-associated names in 85% of cases and female-associated names in only 11.1% of cases.
This study conducts a case survey study based on the secondary data of the major pivots happened in 49 software startups, and demonstrates that customer need pivot is the most common among all pivot types.
Sohaib Shahid Bajwa, Xiaofeng Wang, Anh Nguyen-Duc et al.· Empirical Software Engineeri...· 127 citations· ⚡15
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
MIT News · Artificial Intelligence· news.mit.eduOct 7, 2026
Students in MIT’s Concourse program delve deeply into the human condition, debate challenging questions, and learn to develop judgment about issues that can’t be quantified.
Training AI agents with reinforcement learning can be challenging because their tools, context, and decision-making are managed by complex frameworks. Agent Lightning connects existing agents to RL training, making it easier to improve them without rebuilding them. The post Agent Lightning v1.0: A 3,500-Line Lightweight Agentic RL Framework for Training Agents with Real Harnesses appeared first on Microsoft Research.
MIT News · Artificial Intelligence· news.mit.eduOct 6, 2026