TL;DR
The docking results show that cinnamic acid, 3-phenyl propanoic acid and 3-(4-benzoylphenyl) propanoic acid are predict to have activity as COX-2 inhibitors.
Polypeptide-K (PPK) significantly suppressed NO and PGE2-associated pathways, reducing acute inflammatory reactions in diabetic rats using the paw edema model.
Aim: The present study was undertaken to evaluate the anti-inflammatory activity of various extracts of Mussaenda philippica using the carrageenan – induced paw edema model in albino wistar rats. Methodology: The shade dried leaves plant powder was extracted it various solvents like Benzene, Diethyl ether and Chlorofo...
Inflammation underlies many chronic diseases, and conventional anti-inflammatory drugs are limited by adverse effects and cost. Piliostigma reticulatum is used in African traditional medicine for inflammatory conditions, yet its leaves have not been pharmacologically evaluated. This study investigated the anti-inflamma...
Evaluation of analgesic and anti-inflammatory activity demonstrated that test compound 1, significantly prolonged response latency in the hot plate method, reduced the number of abdominal writhes induced by 1% acetic acid, decreased carrageenan- and formalin- and formalin-induced paw edema, and reduced the volume of ex...
Acetaminophen (APAP) overdose is associated with oxidative stress and injury to the liver and kidney. This study evaluated the antioxidant, hepatoprotective, and nephroprotective effects of an ethyl acetate extract of Persea americana seed in male Wistar rats. Thirty adult male rats were randomly assigned to six groups...
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