Review

Integrative multi-omics reveals NQO1-mediated airway epithelial injury as a key mechanism of bisphenol A-induced COPD.

Rui Li Shaobo Ge Jin Liu Yue Li Shiyuan Yao Shuhan Ma Yuanliang Sun Xiao Li Xia Yang Jie Zhang Ming Zhang

Jul 2026 · Naunyn-Schmiedeberg's Archives of Pharmacology · 0 citations · 32 references

Medicine

TL;DR

It is suggested that BPA is a potential risk factor for COPD, and downregulation of NQO1 contributes to the pathogenesis of BPA-induced COPD, potentially through mitochondrial damage in airway epithelial cells.

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