Lipid Profile Abnormalities in patients with Kidney Failure: A Comparative Study
Abstract
Dyslipidemia has been emerged as a major contributing factor to the close association between (CKD) and a higher chance of developing cardiovascular disease. A condition of lipid metabolism brought on by a combination of hereditary and environmental factors called dyslipidemia. This study examines how patients with renal failure differ from healthy people in terms of their biochemical lipid profiles. The study, which involved 28 participants—14 with renal failure receiving dialysis and 14 healthy controls—was carried out at the Al-Ramadi Educational Hospital in Iraq. Utilizing normal biochemical techniques, serum samples were examined for triglycerides, total cholesterol, HDL, and LDL. In order to evaluate dyslipidemia linked to renal disease, this study looked at the lipid profiles of 28 people, including both healthy persons and patients with kidney failure (ages 25–73). Important conclusions include: TG levels in kidney failure patients were significantly higher than the usual fasting range (<150 mg/dL), with a mean of 271.1 mg/dL. In patients with renal failure, the mean total cholesterol was higher (~216.4 mg/dL) and more variable than in controls (193.1 mg/dL). individuals suffering from chronic kidney disease and end-stage renal disease had considerably decreased HDL values. Patients with renal failure had higher LDL levels on average (~27 mg/dL difference), while there was a greater range with some values as high as 192.8 mg/dL.