An Automated Multivariate EEG Signal Analysis Framework for Seizure Detection Using D-MVMD and BO-SVM.

Abstract

The epileptic seizure (ES) is one of the most prominent neurological conditions, whose detection and classification from the electroencephalogram (EEG) signals is crucial for effective diagnosis of seizures, thereby eliminating the detrimental effects associated with it. However, the development of an automated ES detection system is hindered by the non-stationary, non-linear, and high-dimensional nature of the EEG signals, compounded by noise contamination and inter-subject variability. To address these challenges, this paper proposes an automated ES detection framework based on the De-mixing Multivariate Variational Mode Decomposition (D-MVMD) integrated with the Bayesian Optimized Support Vector Machine (BO-SVM). The D-MVMD decomposes multichannel EEG signals into band-limited intrinsic mode functions (BIMFs) while alleviating the correlation between corresponding modes through an ensemble correlation coefficient, while preserving the seizure characteristics from contamination. Multi-domain features capturing temporal, spectral, and non-linear dynamics of seizure activity are then extracted from the de-mixed BIMFs. ReliefF-ranked random forest-based feature selection is employed to find discriminative features, which are subsequently classified using the optimally tuned BO-SVM classifier. Experimental evaluation on the CHB-MIT demonstrates superior performance, with an accuracy of 98.52%, precision of 98.67%, sensitivity of 98.54%, specificity of 98.54%, and F1 score of 0.98. The model is also evaluated on the Siena dataset to assess its robustness across recording sessions of the same patient. Further, it is analyzed with other state-of-the-art methods, confirming its superior mode separation and enhanced seizure detection. Hence, this developed model proves itself to be an effective and robust model for detecting seizures using the multichannel EEG analysis.