Aug 2026· The journal of prevention of Alzheimer's disease· Vol 13, pp. 100657· 1 citation· ⚡ 1 influential· 69 references
Medicine
Abstract
Highlights • Midlife mNCD provides a critical window for brain health risk modification.• Formalised interventions and self-directed strategies report benefits to cognitive function and psychological well-being.• Engagement with these strategies is influenced by a complex interplay of psychological, cognitive, and logistical factors, as well as social determinants of health.• Equity gaps limit real-world brain health reach, engagement, and scalability.
Key Points Question Is daily step count associated with mental health, academic performance, and brain structure in early adolescents? Findings In this cohort study of 5515 adolescent participants (aged 12 years) outfitted with step counters, higher daily step count was associated with better mental health in a dose-re...
Qing-Yang Li, Amanda E. Paluch, D. Rakesh· JAMA Network Open· 0 citations
Cognitive reserve is one component of brain resilience and may be supported by educational, occupational, and leisure experiences and may be supported by educational, occupational, and leisure experiences.
M. Ordin, Angel Barrasa, Caridad López-Granero et al.· Brain and Behavior· 0 citations
This narrative review evaluated current evidence on the effects of exercise on executive function recovery in individuals with MDD, identified exercise characteristics associated with the greatest cognitive benefits, and summarized the underlying neurobiological mechanisms.
Apathy is a common, disabling, and frequently under-recognised neuropsychiatric syndrome characterised by a quantitative reduction in goal-directed behaviour, cognition, and emotional engagement. It occurs across a broad range of neurological and psychiatric disorders, yet is routinely conflated with depression, cognit...
Vaidya Bala· HSOA Journal of Brain &...· 0 citations
Though depression is a common and debilitating mental health disorder, little is known about its underlying neural mechanisms. In efforts to understand mechanisms, existing research has investigated anhedonia, a core symptom of depression, by focusing on neural correlates of reward processing, which is often assessed v...
Neurocognitive disorders-including mild cognitive impairment, dementia, and delirium-are common yet often underrecognized in heart failure, impairing self-care and outcomes. These heart failure-related neurocognitive disorders pose a significant public health challenge due to high morbidity and mortality. Despite recen...
