TL;DR
Findings reveal a potential role for BPA in POI pathogenesis through the regulation of miRNAs and the cell cycle protein CCND1, providing a novel perspective on the mechanisms underlying this disorder.
It is revealed that miR-234-3p inhibits OC progression by directly targeting WNK2 and thereby attenuating the Ras/MEK/ERK/ERG pathway.
Combining standard endometriosis treatments with exosome-mediated miR-22-3p targeting of p53 could restore p53 function, induce apoptosis, and reduce disease recurrence, providing a promising therapeutic strategy for endometriosis management.
Within the present study, the objective was to investigate the effects of exosomal miR-145-5p on the proliferation, migration and invasion of papillary thyroid cancer (PTC) cells, and explore the molecular mechanism involved. Bioinformatics analyses based on numerous public databases were conducted to profile the expre...
Triple-negative breast cancer (TNBC) is widely considered as one of the most challenging and aggressive forms of breast cancer with poor prognosis and limited treatment options. TNBC progression is associated with aberrant dysregulation of microRNAs (miRNAs) and oncogenic pathways like PI3K/AKT, which promote cell prol...
Epithelial ovarian cancer (EOC) is a highly lethal malignant tumor, with a poor clinical prognosis due to its early peritoneal metastasis. However, the molecular mechanism driving this malignant spread has not been elucidated. In this study, by aggregating the post-transcriptional regulatory network mediated by long no...
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