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Dopaminergic‐ and Cholinergic‐Related Structural MRI Patterns Across Cognitive Subtypes of Parkinson's Disease With Mild Cognitive Impairment

Xue-Qin Bai Hao-Xin Chen Qiu-Yue Li Shi-Wei Zhang Shuangli Chen Andan Qian Rong-Hui Zhou Yi-Tong Cheng Cheng-Long Xie Zhen Wang Yun-Jun Yang Mei-Hao Wang

Sep 2026 · European Journal of Neurology · Vol 33 · 0 citations · 31 references

Medicine

Abstract

The dual syndrome hypothesis distinguishes frontostriatal and posterior cortical cognitive subtypes in Parkinson's disease with mild cognitive impairment (PD‐MCI), which are associated with distinct cognitive profiles and different risks of dementia.

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